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Search Results for " cholesteryl ester transfer protein "

17

Compounds

Cat No. Product Name Synonyms Targets
T2499 Torcetrapib CP-529414 CETP
Torcetrapib (CP-529414) is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torcetrapib failed in phase III trials due to exces...
T6262 Evacetrapib LY2484595 CETP
Evacetrapib (LY2484595) (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.
T1928 Anacetrapib MK-0859 CETP
Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL th...
T6048 Dalcetrapib JTT-705,RO4607381 CETP
Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol.
T28225 Obicetrapib TA8995,AMG899,Obicetrapib (free base),AMG 899,AMG-899,Obicetrapib,TA-8995 CETP
Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.
T68416 DRL-17822
DRL-17822 is a Cholesteryl Ester Transfer Protein (CETP) inhibitor.
T14976 CKD-519 Others
CKD-519 is a selective inhibitor of cholesteryl ester transfer protein (CETP). It inhibits CETP-mediated transfer of cholesteryl ester in human serum (IC50: 2.3 nM).
T68265 PF-04445597
PF-04445597 is a potent, orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP).
T39137 CETP-IN-4
CETP-IN-4 is a cholesteryl ester transfer protein (CETP) inhibitor.
T69672 MK-825
MK-825 is a cholesteryl ester transfer protein (CETP) inhibitor.
T36139 BMS-795311
Potent cholesteryl ester transfer protein (CETP) inhibitor (IC50 = 4 nM in an enzyme-based scintillation proximity assay). Inhibits cholesteryl ester transfer and increases HDL-C levels in vivo. Orally bioavailable. Qiao...
T13079 TAP311 CETP
TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM).
TN5057 Stachybotramide LDL
Stachybotramide preferentially stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to both very low density lipoprotein (VLDL) a...
T68505 Obicetrapib sodium
Obicetrapib sodium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial ...
T68504 Obicetrapib calcium
Obicetrapib calcium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial...
T68503 Obicetrapib potassium
Obicetrapib potassium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible benefici...
T38908 MK-8262
MK-8262, an orally active and potent cholesteryl ester transfer protein (CETP) inhibitor (IC 50 = 53 nM, log D = 5.3), is a bistrifluoromethyl analogue that shows promise in research related to high-density lipoprotein (...
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